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Viral infection of human neurons triggers strain-specific differences in host neuronal and viral transcriptomes

Infection with herpes simplex virus 1 (HSV-1) occurs in over half the global population, causing recurrent orofacial and/or genital lesions. Individual strains of HSV-1 demonstrate differences in neurovirulence in vivo, suggesting that viral genetic differences may impact phenotype. Here differentia...

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Detalles Bibliográficos
Autores principales: Mangold, Colleen A., Rathbun, Molly M., Renner, Daniel W., Kuny, Chad V., Szpara, Moriah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016332/
https://www.ncbi.nlm.nih.gov/pubmed/33750985
http://dx.doi.org/10.1371/journal.ppat.1009441