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Viral infection of human neurons triggers strain-specific differences in host neuronal and viral transcriptomes
Infection with herpes simplex virus 1 (HSV-1) occurs in over half the global population, causing recurrent orofacial and/or genital lesions. Individual strains of HSV-1 demonstrate differences in neurovirulence in vivo, suggesting that viral genetic differences may impact phenotype. Here differentia...
Autores principales: | Mangold, Colleen A., Rathbun, Molly M., Renner, Daniel W., Kuny, Chad V., Szpara, Moriah L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016332/ https://www.ncbi.nlm.nih.gov/pubmed/33750985 http://dx.doi.org/10.1371/journal.ppat.1009441 |
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