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Discovery of a Remarkable Methyl Shift Effect in the Vanilloid Activity of Triterpene Amides
[Image: see text] As part of a study on triterpenoid conjugates, the dietary pentacyclic triterpenoids oleanolic (2a) and ursolic acids (3a) were coupled with vanillamine, and the resulting amides (2b and 3b, respectively) were assayed for activity on the vanilloid receptor TRPV1. Despite a structur...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society and American
Society of Pharmacognosy
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016363/ https://www.ncbi.nlm.nih.gov/pubmed/33136399 http://dx.doi.org/10.1021/acs.jnatprod.0c00639 |