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DeMaSk: a deep mutational scanning substitution matrix and its use for variant impact prediction
MOTIVATION: Accurately predicting the quantitative impact of a substitution on a protein’s molecular function would be a great aid in understanding the effects of observed genetic variants across populations. While this remains a challenging task, new approaches can leverage data from the increasing...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016454/ https://www.ncbi.nlm.nih.gov/pubmed/33325500 http://dx.doi.org/10.1093/bioinformatics/btaa1030 |