Sparse Project VCF: efficient encoding of population genotype matrices

SUMMARY: Variant Call Format (VCF), the prevailing representation for germline genotypes in population sequencing, suffers rapid size growth as larger cohorts are sequenced and more rare variants are discovered. We present Sparse Project VCF (spVCF), an evolution of VCF with judicious entropy reduct...

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Detalles Bibliográficos
Autores principales: Lin, Michael F, Bai, Xiaodong, Salerno, William J, Reid, Jeffrey G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016461/
https://www.ncbi.nlm.nih.gov/pubmed/33300997
http://dx.doi.org/10.1093/bioinformatics/btaa1004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016461/
https://www.ncbi.nlm.nih.gov/pubmed/33300997
http://dx.doi.org/10.1093/bioinformatics/btaa1004

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