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Effects of variable versus nonvariable controlled mechanical ventilation on pulmonary inflammation in experimental acute respiratory distress syndrome in pigs

BACKGROUND: Mechanical ventilation with variable tidal volumes (V(T)) may improve lung function and reduce ventilator-induced lung injury in experimental acute respiratory distress syndrome (ARDS). However, previous investigations were limited to less than 6 h, and control groups did not follow clin...

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Detalles Bibliográficos
Autores principales: Wittenstein, Jakob, Scharffenberg, Martin, Braune, Anja, Huhle, Robert, Bluth, Thomas, Herzog, Moritz, Güldner, Andreas, Ball, Lorenzo, Simonassi, Francesca, Zeidler-Rentzsch, Ines, Vidal Melo, Marcos F., Koch, Thea, Rocco, Patricia R.M., Pelosi, Paolo, Kotzerke, Jörg, Gama de Abreu, Marcelo, Kiss, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: British Journal of Anaesthesia. Published by Elsevier Ltd. 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016484/
https://www.ncbi.nlm.nih.gov/pubmed/32033744
http://dx.doi.org/10.1016/j.bja.2019.12.040