Cargando…

The Role of Unfolded Protein Response in Human Intervertebral Disc Degeneration: Perk and IRE1-α as Two Potential Therapeutic Targets

Inflammation plays a key role in intervertebral disc degeneration (IDD). The association between inflammation and endoplasmic reticulum (ER) stress has been observed in many diseases. However, whether ER stress plays an important role in IDD remains unclear. Therefore, this study is aimed at investi...

Descripción completa

Detalles Bibliográficos
Autores principales: Wen, Tianyong, Xue, Peng, Ying, Jinwei, Cheng, Shi, Liu, Yue, Ruan, Dike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016586/
https://www.ncbi.nlm.nih.gov/pubmed/33833850
http://dx.doi.org/10.1155/2021/6492879