SCARF1 promotes M2 polarization of Kupffer cells via calcium‐dependent PI3K‐AKT‐STAT3 signalling to improve liver transplantation

OBJECTIVES: This study aimed to investigate the protective effect of SCARF1 on acute rejection (AR), phagocytic clearance of Kupffer cells (KCs), M2 polarization and the exact mechanism underlying these processes. METHODS: AAV was transfected into the portal vein of rats, and AR and immune tolerance...

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Detalles Bibliográficos
Autores principales: Xu, Xue‐song, Feng, Zhi‐hao, Cao, Ding, Wu, Hao, Wang, Meng‐hao, Li, Jin‐Zheng, Gong, Jian‐Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016636/
https://www.ncbi.nlm.nih.gov/pubmed/33686740
http://dx.doi.org/10.1111/cpr.13022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016636/
https://www.ncbi.nlm.nih.gov/pubmed/33686740
http://dx.doi.org/10.1111/cpr.13022

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