Large‐scale generation of megakaryocytes from human embryonic stem cells using transgene‐free and stepwise defined suspension culture conditions

OBJECTIVES: Ex vivo engineered production of megakaryocytes (MKs) and platelets (PLTs) from human pluripotent stem cells is an alternative approach to solve shortage of donor‐donated PLTs in clinics and to provide induced PLTs for transfusion. However, low production yields are observed and the gene...

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Detalles Bibliográficos
Autores principales: Zhang, Bowen, Wu, Xumin, Zi, Guicheng, He, Lijuan, Wang, Sihan, Chen, Lin, Fan, Zeng, Nan, Xue, Xi, Jiafei, Yue, Wen, Wang, Lei, Wang, Liu, Hao, Jie, Pei, Xuetao, Li, Yanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016648/
https://www.ncbi.nlm.nih.gov/pubmed/33615584
http://dx.doi.org/10.1111/cpr.13002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016648/
https://www.ncbi.nlm.nih.gov/pubmed/33615584
http://dx.doi.org/10.1111/cpr.13002

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