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TSP50 promotes hepatocyte proliferation and tumour formation by activating glucose‐6‐phosphate dehydrogenase (G6PD)

BACKGROUND & AIMS: Hepatocellular carcinoma (HCC) is a common malignant tumour with high morbidity and mortality. Metabolic regulation by oncogenes is necessary for tumour growth. Testes‐specific protease 50 (TSP50) has been found to promote cell proliferation in multiple tumour types. However,...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaojun, Gao, Feng, Ai, Huihan, Wang, Shuyue, Song, Zhenbo, Zheng, Lihua, Wang, Guannan, Sun, Ying, Bao, Yongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016650/
https://www.ncbi.nlm.nih.gov/pubmed/33630390
http://dx.doi.org/10.1111/cpr.13015