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DNA-driven condensation assembles the meiotic DNA break machinery
Accurate segregation of chromosomes during meiosis—critical for genome stability across sexual cycles—relies on homologous recombination initiated by DNA double-strand breaks (DSBs) made by the Spo11 protein(1,2). DSB formation is regulated and tied to the elaboration of large-scale chromosome struc...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016751/ https://www.ncbi.nlm.nih.gov/pubmed/33731927 http://dx.doi.org/10.1038/s41586-021-03374-w |