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Nicotine Population Pharmacokinetics in Healthy Smokers After Intravenous, Oral, Buccal and Transdermal Administration

BACKGROUND: In 4 decades, numerous nicotine replacement therapy products have been developed. Population pharmacokinetic models can support exposure–response modeling and inform nicotine replacement therapy product development, but only limited model-based cross-study population pharmacokinetic anal...

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Detalles Bibliográficos
Autores principales: Olsson Gisleskog, Per O., Perez Ruixo, Juan José, Westin, Åke, Hansson, Anna C., Soons, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016787/
https://www.ncbi.nlm.nih.gov/pubmed/33354734
http://dx.doi.org/10.1007/s40262-020-00960-5