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Description of the genetic variants identified in a cohort of patients diagnosed with localized anal squamous cell carcinoma and treated with panitumumab

Squamous cell carcinoma is the most frequent histologic type of anal carcinoma. The standard of care since the 1970s has been a combination of 5-fluorouracil, mitomycin C, and radiotherapy. This treatment is very effective in T1/T2 tumors (achieving complete regression in 80–90% of tumors). However,...

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Detalles Bibliográficos
Autores principales: Trilla-Fuertes, Lucía, Gámez-Pozo, Angelo, Maurel, Joan, Garcia-Carbonero, Rocio, Capdevila, Jaume, G-Pastrián, Laura, Mendiola, Marta, Peña, Cristina, López-Vacas, Rocío, Cuatrecasas, Miriam, García-Alfonso, Pilar, Ramos-Ruiz, Ricardo, Llorens, Carlos, Ghanem, Ismael, Conill, Carles, Heredia-Soto, Victoria, Campos-Barros, Ángel, Fresno Vara, Juan Ángel, Feliu, Jaime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016846/
https://www.ncbi.nlm.nih.gov/pubmed/33795829
http://dx.doi.org/10.1038/s41598-021-86966-w