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Human skin aging is associated with increased expression of the histone variant H2A.J in the epidermis

Cellular senescence is an irreversible growth arrest that occurs as a result of damaging stimuli, including DNA damage and/or telomere shortening. Here, we investigate histone variant H2A.J as a new biomarker to detect senescent cells during human skin aging. Skin biopsies from healthy volunteers of...

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Detalles Bibliográficos
Autores principales: Rübe, Claudia E., Bäumert, Caroline, Schuler, Nadine, Isermann, Anna, Schmal, Zoé, Glanemann, Matthias, Mann, Carl, Scherthan, Harry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016850/
https://www.ncbi.nlm.nih.gov/pubmed/33795696
http://dx.doi.org/10.1038/s41514-021-00060-z