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Cost-effectiveness of CYP2C19 genotyping to guide antiplatelet therapy for acute minor stroke and high-risk transient ischemic attack

Dual antiplatelet therapy (DAPT) with clopidogrel plus aspirin within 48 h of acute minor strokes and transient ischemic attacks (TIAs) has been indicated to effectively reduce the rate of recurrent strokes. However, the efficacy of clopidogrel has been shown to be affected by cytochrome P450 2C19 (...

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Detalles Bibliográficos
Autores principales: Cai, Zeling, Cai, De, Wang, Ruiwen, Wang, Heng, Yu, Ze, Gao, Fei, Liu, Yuansheng, Kang, Yingbo, Wu, Zhuomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016871/
https://www.ncbi.nlm.nih.gov/pubmed/33795788
http://dx.doi.org/10.1038/s41598-021-86824-9