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A KRAS-responsive long non-coding RNA controls microRNA processing

Wild-type KRAS (KRAS(WT)) amplification has been shown to be a secondary means of KRAS activation in cancer and associated with poor survival. Nevertheless, the precise role of KRAS(WT) overexpression in lung cancer progression is largely unexplored. Here, we identify and characterize a KRAS-respons...

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Detalles Bibliográficos
Autores principales: Shi, Lei, Magee, Peter, Fassan, Matteo, Sahoo, Sudhakar, Leong, Hui Sun, Lee, Dave, Sellers, Robert, Brullé-Soumaré, Laura, Cairo, Stefano, Monteverde, Tiziana, Volinia, Stefano, Smith, Duncan D., Di Leva, Gianpiero, Galuppini, Francesca, Paliouras, Athanasios R., Zeng, Kang, O’Keefe, Raymond, Garofalo, Michela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016872/
https://www.ncbi.nlm.nih.gov/pubmed/33795683
http://dx.doi.org/10.1038/s41467-021-22337-3