Cargando…

Wnt5a promotes hippocampal postsynaptic development and GluN2B-induced expression via the eIF2α HRI kinase

Wnt signaling plays a key role in neurodevelopment and neuronal maturation. Specifically, Wnt5a stimulates postsynaptic assemblies, increases glutamatergic neurotransmission and, through calcium signaling, generates nitric oxide (NO). Trying to unveil the molecular pathway triggering these postsynap...

Descripción completa

Detalles Bibliográficos
Autores principales: Ramos-Fernández, Eva, Arrázola, Macarena S., Oliva, Carolina A., Arredondo, Sebastián B., Varela-Nallar, Lorena, Inestrosa, Nibaldo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016897/
https://www.ncbi.nlm.nih.gov/pubmed/33795747
http://dx.doi.org/10.1038/s41598-021-86708-y