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Wnt5a promotes hippocampal postsynaptic development and GluN2B-induced expression via the eIF2α HRI kinase
Wnt signaling plays a key role in neurodevelopment and neuronal maturation. Specifically, Wnt5a stimulates postsynaptic assemblies, increases glutamatergic neurotransmission and, through calcium signaling, generates nitric oxide (NO). Trying to unveil the molecular pathway triggering these postsynap...
Autores principales: | Ramos-Fernández, Eva, Arrázola, Macarena S., Oliva, Carolina A., Arredondo, Sebastián B., Varela-Nallar, Lorena, Inestrosa, Nibaldo C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016897/ https://www.ncbi.nlm.nih.gov/pubmed/33795747 http://dx.doi.org/10.1038/s41598-021-86708-y |
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