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Suppression of TGF-β1 signaling by Matrigel via FAK signaling in cultured human trabecular meshwork cells

The trabecular meshwork (TM) is composed of TM cells and beams of the extracellular matrix, together contributing to aqueous humor (AH) outflow resistance. Herein, we validated that our culture system on 2D Matrigel expressed putative TM markers and myocilin, of which the latter was upregulated by d...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan, Tseng, Scheffer C. G., Zhu, Ying-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016910/
https://www.ncbi.nlm.nih.gov/pubmed/33795740
http://dx.doi.org/10.1038/s41598-021-86591-7