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Activation of NF-κB signaling via cytosolic mitochondrial RNA sensing in kerotocytes with mitochondrial DNA common deletion

Scar formation as a result of corneal wound healing is a leading cause of blindness. It is a challenge to understand why scar formation is more likely to occur in the central part of the cornea as compared to the peripheral part. The purpose of this study was to unravel the underlying mechanisms. We...

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Detalles Bibliográficos
Autores principales: Zhou, Xin, Backman, Ludvig J., Danielson, Patrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016944/
https://www.ncbi.nlm.nih.gov/pubmed/33795727
http://dx.doi.org/10.1038/s41598-021-86522-6