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Skeletal muscle fibers play a functional role in host defense during sepsis in mice

Skeletal muscles secrete a wide variety of immunologically active cytokines, but the functional significance of this response to in vivo innate immunity is not understood. We addressed this by knocking out the toll receptor adapter protein, Myd88, only in skeletal muscle fibers (skmMyd88KO), and fol...

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Detalles Bibliográficos
Autores principales: Laitano, Orlando, Robinson, Gerard P., Murray, Kevin O., Garcia, Christian K., Mattingly, Alex J., Morse, Deborah, King, Michelle A., Iwaniec, John D., Alzahrani, Jamal M., Clanton, Thomas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016959/
https://www.ncbi.nlm.nih.gov/pubmed/33795743
http://dx.doi.org/10.1038/s41598-021-86585-5