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Systematic prediction of drug resistance caused by transporter genes in cancer cells
To study the drug resistance problem caused by transporters, we leveraged multiple large-scale public data sets of drug sensitivity, cell line genetic and transcriptional profiles, and gene silencing experiments. Through systematic integration of these data sets, we built various machine learning mo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016963/ https://www.ncbi.nlm.nih.gov/pubmed/33795761 http://dx.doi.org/10.1038/s41598-021-86921-9 |