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Growth hormone induces mitotic catastrophe of glomerular podocytes and contributes to proteinuria

Glomerular podocytes are integral members of the glomerular filtration barrier in the kidney and are crucial for glomerular permselectivity. These highly differentiated cells are vulnerable to an array of noxious stimuli that prevail in several glomerular diseases. Elevated circulating growth hormon...

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Detalles Bibliográficos
Autores principales: Nishad, Rajkishor, Mukhi, Dhanunjay, Singh, Ashish Kumar, Motrapu, Manga, Chintala, Kumaraswami, Tammineni, Prasad, Pasupulati, Anil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016968/
https://www.ncbi.nlm.nih.gov/pubmed/33795655
http://dx.doi.org/10.1038/s41419-021-03643-6