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Linking the YTH domain to cancer: the importance of YTH family proteins in epigenetics

N6-methyladenosine (m6A), the most prevalent and reversible modification of mRNA in mammalian cells, has recently been extensively studied in epigenetic regulation. YTH family proteins, whose YTH domain can recognize and bind m6A-containing RNA, are the main “readers” of m6A modification. YTH family...

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Detalles Bibliográficos
Autores principales: Shi, Rongkai, Ying, Shilong, Li, Yadan, Zhu, Liyuan, Wang, Xian, Jin, Hongchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016981/
https://www.ncbi.nlm.nih.gov/pubmed/33795663
http://dx.doi.org/10.1038/s41419-021-03625-8