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Antibody–drug nanoparticle induces synergistic treatment efficacies in HER2 positive breast cancer cells

Chemotherapeutic drugs suffer from non-specific binding, undesired toxicity, and poor blood circulation which contribute to poor therapeutic efficacy. In this study, antibody–drug nanoparticles (ADNs) are engineered by synthesizing pure anti-cancer drug nanorods (NRs) in the core of nanoparticles wi...

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Detalles Bibliográficos
Autores principales: Abedin, Muhammad Raisul, Powers, Kaitlyne, Aiardo, Rachel, Barua, Dibbya, Barua, Sutapa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016985/
https://www.ncbi.nlm.nih.gov/pubmed/33795712
http://dx.doi.org/10.1038/s41598-021-86762-6