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Evolution of DNA methylation in the human brain

DNA methylation is a critical regulatory mechanism implicated in development, learning, memory, and disease in the human brain. Here we have elucidated DNA methylation changes during recent human brain evolution. We demonstrate dynamic evolutionary trajectories of DNA methylation in cell-type and cy...

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Detalles Bibliográficos
Autores principales: Jeong, Hyeonsoo, Mendizabal, Isabel, Berto, Stefano, Chatterjee, Paramita, Layman, Thomas, Usui, Noriyoshi, Toriumi, Kazuya, Douglas, Connor, Singh, Devika, Huh, Iksoo, Preuss, Todd M., Konopka, Genevieve, Yi, Soojin V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017017/
https://www.ncbi.nlm.nih.gov/pubmed/33795684
http://dx.doi.org/10.1038/s41467-021-21917-7