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Evolution of DNA methylation in the human brain
DNA methylation is a critical regulatory mechanism implicated in development, learning, memory, and disease in the human brain. Here we have elucidated DNA methylation changes during recent human brain evolution. We demonstrate dynamic evolutionary trajectories of DNA methylation in cell-type and cy...
Autores principales: | Jeong, Hyeonsoo, Mendizabal, Isabel, Berto, Stefano, Chatterjee, Paramita, Layman, Thomas, Usui, Noriyoshi, Toriumi, Kazuya, Douglas, Connor, Singh, Devika, Huh, Iksoo, Preuss, Todd M., Konopka, Genevieve, Yi, Soojin V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017017/ https://www.ncbi.nlm.nih.gov/pubmed/33795684 http://dx.doi.org/10.1038/s41467-021-21917-7 |
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