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Sweroside Protects Against Myocardial Ischemia–Reperfusion Injury by Inhibiting Oxidative Stress and Pyroptosis Partially via Modulation of the Keap1/Nrf2 Axis

Aims: Sweroside, a secoiridoid glucoside extracted from Swertia pseudochinensis Hara, is reported to possess antioxidant and anti-inflammatory activities. However, whether sweroside has a protective effect on myocardial ischemia–reperfusion (IR) injury is yet to be elucidated. The present study aime...

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Detalles Bibliográficos
Autores principales: Li, Jun, Zhao, Cuiting, Zhu, Qing, Wang, Yonghuai, Li, Guangyuan, Li, Xinxin, Li, Yuhong, Wu, Nan, Ma, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017130/
https://www.ncbi.nlm.nih.gov/pubmed/33816579
http://dx.doi.org/10.3389/fcvm.2021.650368