Insight Into Seeded Tau Fibril Growth From Molecular Dynamics Simulation of the Alzheimer’s Disease Protofibril Core

Aggregates of the microtubule associated tau protein are a major constituent of neurofibrillary lesions that define Alzheimer’s disease (AD) pathology. Increasing experimental evidence suggests that the spread of tau neurofibrillary tangles results from a prion-like seeding mechanism in which small...

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Detalles Bibliográficos
Autores principales: Leonard, Cass, Phillips, Christian, McCarty, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017153/
https://www.ncbi.nlm.nih.gov/pubmed/33816551
http://dx.doi.org/10.3389/fmolb.2021.624302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017153/
https://www.ncbi.nlm.nih.gov/pubmed/33816551
http://dx.doi.org/10.3389/fmolb.2021.624302

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