Pharmacological and Genetic Inhibition of PD-1 Demonstrate an Important Role of PD-1 in Ischemia-Induced Skeletal Muscle Inflammation, Oxidative Stress, and Angiogenesis

Angiogenesis is an important process under both physiological and pathophysiological conditions. Here we investigated the role and the underlying mechanism of PD-1 in hindlimb ischemia-induced inflammation and angiogenesis in mice. We found that inhibition of PD-1 by genetic PD-1 knockout or pharmac...

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Detalles Bibliográficos
Autores principales: Liu, Xiaoguang, Weng, Xinyu, Xiao, Weihua, Xu, Xin, Chen, Yingjie, Chen, Peijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017157/
https://www.ncbi.nlm.nih.gov/pubmed/33815358
http://dx.doi.org/10.3389/fimmu.2021.586429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017157/
https://www.ncbi.nlm.nih.gov/pubmed/33815358
http://dx.doi.org/10.3389/fimmu.2021.586429

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