Pathophysiological Relevance of Renal Medullary Conditions on the Behaviour of Red Cells From Patients With Sickle Cell Anaemia

Red cells from patients with sickle cell anaemia (SCA) contain the abnormal haemoglobin HbS. Under hypoxic conditions, HbS polymerises and causes red cell sickling, a rise in intracellular Ca(2+) and exposure of phosphatidylserine (PS). These changes make sickle cells sticky and liable to lodge in t...

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Detalles Bibliográficos
Autores principales: Lu, David C.-Y., Wadud, Rasiqh, Hannemann, Anke, Rees, David C., Brewin, John N., Gibson, John Stanley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017214/
https://www.ncbi.nlm.nih.gov/pubmed/33815154
http://dx.doi.org/10.3389/fphys.2021.653545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017214/
https://www.ncbi.nlm.nih.gov/pubmed/33815154
http://dx.doi.org/10.3389/fphys.2021.653545

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