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Immune Responses Following BCG Immunization of Infants in Uganda and United Kingdom Are Similar for Purified Protein Derivative but Differ for Secretory Proteins of Mycobacterium tuberculosis

Introduction: The immunogenicity of BCG vaccination in infants differs between populations. We hypothesized that prenatal exposure to mycobacterial antigens might explain the differences in immune responses to BCG seen in other studies of infants in Africa and the United Kingdom (UK) and we explored...

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Detalles Bibliográficos
Autores principales: Mawa, Patrice A., Hasso-Agopsowicz, Mateusz, Lubyayi, Lawrence, Nabakooza, Grace, Nakibuule, Marjorie, Blitz, Rose, Dun, Li, Govind, Abha, Kaleebu, Pontiano, Webb, Emily L., Elliott, Alison M., Dockrell, Hazel M., Cose, Stephen, Smith, Steven G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017231/
https://www.ncbi.nlm.nih.gov/pubmed/33815390
http://dx.doi.org/10.3389/fimmu.2021.637114