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Menthol to Induce Non-shivering Thermogenesis via TRPM8/PKA Signaling for Treatment of Obesity

Increasing basal energy expenditure via uncoupling protein 1 (UCP1)-dependent non-shivering thermogenesis is an attractive therapeutic strategy for treatment of obesity. Transient receptor potential melastatin 8 (TRPM8) channel activation by cold and cold mimetics induces UCP1 transcription and prev...

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Detalles Bibliográficos
Autores principales: Sanders, Owen Davis, Rajagopal, Jayalekshmi Archa, Rajagopal, Lekshmy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for the Study of Obesity 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017329/
https://www.ncbi.nlm.nih.gov/pubmed/33071240
http://dx.doi.org/10.7570/jomes20038