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Validation of Serum Neurofilament Light Chain as a Biomarker of Parkinson’s Disease Progression

BACKGROUND: The objective of this study was to assess neurofilament light chain as a Parkinson’s disease biomarker. METHODS: We quantified neurofilament light chain in 2 independent cohorts: (1) longitudinal cerebrospinal fluid samples from the longitudinal de novo Parkinson’s disease cohort and (2)...

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Detalles Bibliográficos
Autores principales: Mollenhauer, Brit, Dakna, Mohammed, Kruse, Niels, Galasko, Douglas, Foroud, Tatiana, Zetterberg, Henrik, Schade, Sebastian, Gera, Roland G., Wang, Wenting, Gao, Feng, Frasier, Mark, Chahine, Lana M., Coffey, Christopher S., Singleton, Andrew B., Simuni, Tanya, Weintraub, Daniel, Seibyl, John, Toga, Arthur W., Tanner, Caroline M., Kieburtz, Karl, Marek, Kenneth, Siderowf, Andrew, Cedarbaum, Jesse M., Hutten, Samantha J., Trenkwalder, Claudia, Graham, Danielle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017468/
https://www.ncbi.nlm.nih.gov/pubmed/32798333
http://dx.doi.org/10.1002/mds.28206