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Validation of Serum Neurofilament Light Chain as a Biomarker of Parkinson’s Disease Progression
BACKGROUND: The objective of this study was to assess neurofilament light chain as a Parkinson’s disease biomarker. METHODS: We quantified neurofilament light chain in 2 independent cohorts: (1) longitudinal cerebrospinal fluid samples from the longitudinal de novo Parkinson’s disease cohort and (2)...
Autores principales: | Mollenhauer, Brit, Dakna, Mohammed, Kruse, Niels, Galasko, Douglas, Foroud, Tatiana, Zetterberg, Henrik, Schade, Sebastian, Gera, Roland G., Wang, Wenting, Gao, Feng, Frasier, Mark, Chahine, Lana M., Coffey, Christopher S., Singleton, Andrew B., Simuni, Tanya, Weintraub, Daniel, Seibyl, John, Toga, Arthur W., Tanner, Caroline M., Kieburtz, Karl, Marek, Kenneth, Siderowf, Andrew, Cedarbaum, Jesse M., Hutten, Samantha J., Trenkwalder, Claudia, Graham, Danielle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017468/ https://www.ncbi.nlm.nih.gov/pubmed/32798333 http://dx.doi.org/10.1002/mds.28206 |
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