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Comparison of 4-Factor Prothrombin Complex Concentrate With Frozen Plasma for Management of Hemorrhage During and After Cardiac Surgery: A Randomized Pilot Trial

IMPORTANCE: Approximately 15% of patients undergoing cardiac surgery receive frozen plasma (FP) for bleeding. Four-factor prothrombin complex concentrates (PCCs) have logistical and safety advantages over FP and may be a suitable alternative. OBJECTIVES: To determine the proportion of patients who r...

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Detalles Bibliográficos
Autores principales: Karkouti, Keyvan, Bartoszko, Justyna, Grewal, Deep, Bingley, Cielo, Armali, Chantal, Carroll, Jo, Hucke, Hans-Peter, Kron, Amie, McCluskey, Stuart A., Rao, Vivek, Callum, Jeannie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017469/
https://www.ncbi.nlm.nih.gov/pubmed/33792729
http://dx.doi.org/10.1001/jamanetworkopen.2021.3936