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Engineering a Human Pluripotent Stem Cell-Based in vitro Microphysiological System for Studying the Metformin Response in Aortic Smooth Muscle Cells

Aortic aneurysm is a common cardiovascular disease characterised by continuous dilation of the aorta, and this disease places a heavy burden on healthcare worldwide. Few drugs have been suggested to be effective in controlling the progression of aortic aneurysms. Preclinical drug responses from trad...

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Detalles Bibliográficos
Autores principales: Chen, Nan, Abudupataer, Mieradilijiang, Feng, Sisi, Zhu, Shichao, Ma, Wenrui, Li, Jun, Lai, Hao, Zhu, Kai, Wang, Chunsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017487/
https://www.ncbi.nlm.nih.gov/pubmed/33816448
http://dx.doi.org/10.3389/fbioe.2021.627877