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Fast lightweight accurate xenograft sorting

MOTIVATION: With an increasing number of patient-derived xenograft (PDX) models being created and subsequently sequenced to study tumor heterogeneity and to guide therapy decisions, there is a similarly increasing need for methods to separate reads originating from the graft (human) tumor and reads...

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Detalles Bibliográficos
Autores principales: Zentgraf, Jens, Rahmann, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017614/
https://www.ncbi.nlm.nih.gov/pubmed/33810805
http://dx.doi.org/10.1186/s13015-021-00181-w