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Fast lightweight accurate xenograft sorting
MOTIVATION: With an increasing number of patient-derived xenograft (PDX) models being created and subsequently sequenced to study tumor heterogeneity and to guide therapy decisions, there is a similarly increasing need for methods to separate reads originating from the graft (human) tumor and reads...
Autores principales: | Zentgraf, Jens, Rahmann, Sven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017614/ https://www.ncbi.nlm.nih.gov/pubmed/33810805 http://dx.doi.org/10.1186/s13015-021-00181-w |
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