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Determinism and contingencies shaped the evolution of mitochondrial protein import

Mitochondrial protein import requires outer membrane receptors that evolved independently in different lineages. Here we used quantitative proteomics and in vitro binding assays to investigate the substrate preferences of ATOM46 and ATOM69, the two mitochondrial import receptors of Trypanosoma bruce...

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Detalles Bibliográficos
Autores principales: Rout, Samuel, Oeljeklaus, Silke, Makki, Abhijith, Tachezy, Jan, Warscheid, Bettina, Schneider, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017667/
https://www.ncbi.nlm.nih.gov/pubmed/33526678
http://dx.doi.org/10.1073/pnas.2017774118