Cooperativity between the orthosteric and allosteric ligand binding sites of RORγt

Cooperative ligand binding is an important phenomenon in biological systems where ligand binding influences the binding of another ligand at an alternative site of the protein via an intramolecular network of interactions. The underlying mechanisms behind cooperative binding remain poorly understood...

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Detalles Bibliográficos
Autores principales: de Vries, Rens M. J. M., Meijer, Femke A., Doveston, Richard G., Leijten-van de Gevel, Iris A., Brunsveld, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Physical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017705/
https://www.ncbi.nlm.nih.gov/pubmed/33536342
http://dx.doi.org/10.1073/pnas.2021287118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017705/
https://www.ncbi.nlm.nih.gov/pubmed/33536342
http://dx.doi.org/10.1073/pnas.2021287118

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