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Cooperativity between the orthosteric and allosteric ligand binding sites of RORγt
Cooperative ligand binding is an important phenomenon in biological systems where ligand binding influences the binding of another ligand at an alternative site of the protein via an intramolecular network of interactions. The underlying mechanisms behind cooperative binding remain poorly understood...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017705/ https://www.ncbi.nlm.nih.gov/pubmed/33536342 http://dx.doi.org/10.1073/pnas.2021287118 |