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Effect of oxaliplatin plus 5-fluorouracil or capecitabine on circulating and imaging biomarkers in patients with metastatic colorectal cancer: a prospective biomarker study

BACKGROUND: Patients with metastatic colorectal cancer are treated with cytotoxic chemotherapy supplemented by molecularly targeted therapies. There is a critical need to define biomarkers that can optimise the use of these therapies to maximise efficacy and avoid unnecessary toxicity. However, it i...

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Detalles Bibliográficos
Autores principales: Mahmood, Reem D., Shaw, Danielle, Descamps, Tine, Zhou, Cong, Morgan, Robert D., Mullamitha, Saifee, Saunders, Mark, Mescallado, Nerissa, Backen, Alison, Morris, Karen, Little, Ross A., Cheung, Susan, Watson, Yvonne, O’Connor, James P. B., Jackson, Alan, Parker, Geoff J. M., Dive, Caroline, Jayson, Gordon C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017714/
https://www.ncbi.nlm.nih.gov/pubmed/33794823
http://dx.doi.org/10.1186/s12885-021-08097-9