Coronavirus replication–transcription complex: Vital and selective NMPylation of a conserved site in nsp9 by the NiRAN-RdRp subunit

RNA-dependent RNA polymerases (RdRps) of the Nidovirales (Coronaviridae, Arteriviridae, and 12 other families) are linked to an amino-terminal (N-terminal) domain, called NiRAN, in a nonstructural protein (nsp) that is released from polyprotein 1ab by the viral main protease (M(pro)). Previously, se...

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Detalles Bibliográficos
Autores principales: Slanina, Heiko, Madhugiri, Ramakanth, Bylapudi, Ganesh, Schultheiß, Karin, Karl, Nadja, Gulyaeva, Anastasia, Gorbalenya, Alexander E., Linne, Uwe, Ziebuhr, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017715/
https://www.ncbi.nlm.nih.gov/pubmed/33472860
http://dx.doi.org/10.1073/pnas.2022310118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017715/
https://www.ncbi.nlm.nih.gov/pubmed/33472860
http://dx.doi.org/10.1073/pnas.2022310118

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