Neuropathological and behavioral characterization of aged Grn R493X progranulin-deficient frontotemporal dementia knockin mice

Frontotemporal lobar degeneration (FTLD) causes a spectrum of clinical presentations of frontotemporal dementia (FTD), including progressive changes in behavior, personality, executive function, and language. Up to 20% of familial FTLD cases are caused by progranulin (GRN) haploinsufficiency (FTD-GR...

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Detalles Bibliográficos
Autores principales: Frew, Jonathan, Nygaard, Haakon Berge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017751/
https://www.ncbi.nlm.nih.gov/pubmed/33795008
http://dx.doi.org/10.1186/s40478-021-01158-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017751/
https://www.ncbi.nlm.nih.gov/pubmed/33795008
http://dx.doi.org/10.1186/s40478-021-01158-x

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