Feedback activation of NF-KB signaling leads to adaptive resistance to EZH2 inhibitors in prostate cancer cells

BACKGROUND: Prostate cancer (PCa) is the most common malignant tumor in developed countries, which has seriously threatened men’s lifestyle and quality of life. The up-regulation of EZH2 is associated with advanced PCa and poor prognosis, making it a promising therapeutic target. However, the EZH2 i...

Descripción completa

Detalles Bibliográficos
Autores principales: Jin, Mengyuan, Duan, Jiachen, Liu, Wei, Ji, Jing, Liu, Bin, Zhang, Mingzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017762/
https://www.ncbi.nlm.nih.gov/pubmed/33794893
http://dx.doi.org/10.1186/s12935-021-01897-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017762/
https://www.ncbi.nlm.nih.gov/pubmed/33794893
http://dx.doi.org/10.1186/s12935-021-01897-w

Ejemplares similares