The ASXL1-G643Wvariant accelerates the development of CEBPA mutant acute myeloid leukemia

ASXL1 is one of the most commonly mutated genes in myeloid malignancies, including myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). In order to further our understanding of the role of ASXL1 lesions in malignant hematopoiesis, we generated a novel knockin mouse model carrying the mos...

Descripción completa

Detalles Bibliográficos
Autores principales: D’Altri, Teresa, Wilhelmson, Anna S., Schuster, Mikkel B., Wenzel, Anne, Kalvisa, Adrija, Pundhir, Sachin, Hansen, Anne Meldgaard, Porse, Bo T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017816/
https://www.ncbi.nlm.nih.gov/pubmed/32381577
http://dx.doi.org/10.3324/haematol.2019.235150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017816/
https://www.ncbi.nlm.nih.gov/pubmed/32381577
http://dx.doi.org/10.3324/haematol.2019.235150

Ejemplares similares