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Biology and grading of pleomorphic xanthoastrocytoma—what have we learned about it?

Pleomorphic xanthoastrocytoma (PXA) is a rare astrocytoma predominantly affecting children and young adults. We performed comprehensive genomic characterization on a cohort of 67 patients with histologically defined PXA (n = 53, 79%) or anaplastic PXA (A‐PXA, n = 14, 21%), including copy number anal...

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Detalles Bibliográficos
Autores principales: Vaubel, Rachael, Zschernack, Valentina, Tran, Quynh T., Jenkins, Sarah, Caron, Alissa, Milosevic, Dragana, Smadbeck, James, Vasmatzis, George, Kandels, Daniela, Gnekow, Astrid, Kramm, Christof, Jenkins, Robert, Kipp, Benjamin R., Rodriguez, Fausto J., Orr, Brent A., Pietsch, Torsten, Giannini, Caterina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018001/
https://www.ncbi.nlm.nih.gov/pubmed/32619305
http://dx.doi.org/10.1111/bpa.12874