Investigation of pathology, expression and proteomic profiles in human TREM2 variant postmortem brains with and without Alzheimer’s disease

Triggering receptor expressed on myeloid cells 2 TREM2 was identified as a risk factor for late onset Alzheimer’s disease (AD). Here we compared TREM2 cases with a variant (TREM2(+)) and cases without a TREM2 variant (TREM2(−)), considering pathological burden, inflammatory response and altered cano...

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Detalles Bibliográficos
Autores principales: Toomey, Christina E., Heywood, Wendy, Benson, Bridget C., Packham, Georgia, Mills, Kevin, Lashley, Tammaryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018003/
https://www.ncbi.nlm.nih.gov/pubmed/32267026
http://dx.doi.org/10.1111/bpa.12842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018003/
https://www.ncbi.nlm.nih.gov/pubmed/32267026
http://dx.doi.org/10.1111/bpa.12842

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