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Iron accumulation in the choroid plexus, ependymal cells and CNS parenchyma in a rat strain with low‐grade haemolysis of fragile macrocytic red blood cells

Iron accumulation in the CNS is associated with many neurological diseases via amplification of inflammation and neurodegeneration. However, experimental studies on iron overload are challenging, since rodents hardly accumulate brain iron in contrast to humans. Here, we studied LEWzizi rats, which p...

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Detalles Bibliográficos
Autores principales: Wimmer, Isabella, Scharler, Cornelia, Kadowaki, Taro, Hillebrand, Sophie, Scheiber‐Mojdehkar, Barbara, Ueda, Shuichi, Bradl, Monika, Berger, Thomas, Lassmann, Hans, Hametner, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018038/
https://www.ncbi.nlm.nih.gov/pubmed/33220123
http://dx.doi.org/10.1111/bpa.12920